Pre-malignant signs of gastric MALT lymphoma

Authors

  • Renato Takayuki Hassegawa Universidade de São Paulo, Hospital Universitário, Endoscopy Service
  • Eduardo Koji Marchi Ogawa Universidade de São Paulo, Hospital das Clínicas, Endoscopy Service https://orcid.org/0000-0002-1049-8418
  • Roberto El Ibrahim Diagnóstika Surgical Pathology and Cytology
  • Filadelfio Euclides Venco Diagnóstika Surgical Pathology and Cytology
  • Luis Masuo Maruta Universidade de São Paulo, Hospital Universitário, Endoscopy Service

DOI:

https://doi.org/10.4322/acr.2019.130

Keywords:

Lymphoma, B-Cell, Marginal Zone, Endoscopy

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma is the most common type of extra-nodal non-Hodgkin lymphoma, which mostly involves the stomach. The clinical suspicion and diagnosis are often challenging because of the lack of specific symptoms and conventional endoscopic findings. Three magnifying endoscopic signs of the gastric mucosa have been described as highly specific to the diagnosis of MALT lymphoma, such as (i) tree-like appearance of the microvessels; (ii) non-structural area; and (iii) ballooning crypt pattern. We report the case of a middle-aged woman in which these signs appeared chronologically over a period of 2 years, showing the association of the sequence of the endoscopic findings and the final histological diagnosis of gastric MALT lymphoma.

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Published

2020-01-24

Issue

Section

Article / Clinical Case Report

How to Cite

Pre-malignant signs of gastric MALT lymphoma. (2020). Autopsy and Case Reports, 10(1), e2019130. https://doi.org/10.4322/acr.2019.130