Kidney function after left renal vein ligation in the dog

  • Guilherme Velloso Diniz Faculty of Medical Sciences; Laboratory of Experimental Surgery
  • Walter José Fagundes Pereira Faculty of Medical Sciences; Laboratory of Experimental Surgery
  • Ana Cristina Machado Moreira Faculty of Medical Sciences; Laboratory of Experimental Surgery
  • Bruno Mello Rodrigues dos Santos Faculty of Medical Sciences; Laboratory of Experimental Surgery
  • Domingos André Fernandes Drumond Faculty of Medical Sciences; Laboratory of Experimental Surgery
  • Andy Petroianu Faculty of Medical Sciences; Laboratory of Experimental Surgery
Keywords: Renal Vein, Tributaries of the Renal Vein, Trauma, Nephrectomy, Renal Function

Abstract

The ligature of the left renal vein is an alternative whenever this vessel is injured. The purpose of this study was to evaluate the capacity of the affluents of the left renal vein, proximal to the ligature, to maintain tissue vitality and function of the left kidney. Fifteen mongrel male dogs were divided in 3 groups of 5 dogs: Group I (control) - a laparotomy was performed, and the abdominal structures were only identified; Group II - the left renal vein was tied, close to vena cava; Group III - the same procedure as for Group II and a right nephrectomy. Blood urea nitrogen and serum creatinine levels were measured before the procedure, and every 3 days during 4 weeks in the postoperative period. Renal arteriography and an excretory urogram were performed on the animals that survived 60 days. Thereafter, or immediately after precocious death, the kidneys were removed for histological examination. All the animals of Group III died before two months (mean = 10.5 +-3.2 days), while the animals of Group II survived during that period. There was a complete exclusion of the left kidney in all dogs that underwent renal vein ligature. In the animals of Group II, the renal cortico-medullary limits could not be identified. At microscopy, the aspect was suggestive of nephrosclerosis. In the animals of Group III, the left kidney was enlarged, and a great amount of intravascular and intrapelvic blood clots were observed. At microscopy, extensive areas of necrosis, inflammatory infiltration, and hemorrhage were identified. In conclusion, the tributaries of the renal vein were not sufficient to maintain the tissue vitality and function of the left kidney after ligature of its main vein.
Published
2001-01-01
How to Cite
Diniz, G., Pereira, W., Moreira, A., Santos, B., Drumond, D., & Petroianu, A. (2001). Kidney function after left renal vein ligation in the dog . Revista Do Hospital Das Clínicas, 56(1), 1-4. https://doi.org/10.1590/S0041-87812001000100001
Section
Original Articles