Characterization and stability studies of emulsion systems containing pumice

Authors

  • Marilene Estanqueiro University of Porto; Faculty of Pharmacy; Department of Drug Sciences
  • Jaime Conceição University of Porto; Faculty of Pharmacy; Department of Drug Sciences
  • Maria Helena Amaral University of Porto; Faculty of Pharmacy; Department of Drug Sciences
  • Delfim Santos University of Porto; Faculty of Pharmacy; Department of Drug Sciences
  • João Baptista Silva University of Aveiro
  • José Manuel Sousa Lobo University of Porto; Faculty of Pharmacy; Department of Drug Sciences

DOI:

https://doi.org/10.1590/S1984-82502014000200016

Abstract

Emulsions are the most common form of skin care products. However, these systems may exhibit some instability. Therefore, when developing emulsions for topical application it is interesting to verify whether they have suitable physical and mechanical characteristics and further assess their stability. The aim of this work was to study the stability of emulsion systems, which varied in the proportion of the emulsifying agent cetearyl alcohol (and) sodium lauryl sulfate (and) sodium cetearyl sulfate (LSX), the nature of the oily phase (decyl oleate, cyclomethicone or dimethicone) and the presence or absence of pumice (5% w/w). While maintaining the samples at room temperature, rheology studies, texture analysis and microscopic observation of formulations with and without pumice were performed. Samples were also submitted to an accelerated stability study by centrifugation and to a thermal stress test. Through the testing, it was found that the amount of emulsifying agent affects the consistency and textural properties such as firmness and adhesiveness. So, formulations containing LSX (5% w/w) and decyl oleate or dimethicone as oily phase had a better consistency and remained stable with time, so exhibited the best features to be used for skin care products.

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Published

2014-04-01

Issue

Section

Articles

How to Cite

Characterization and stability studies of emulsion systems containing pumice . (2014). Brazilian Journal of Pharmaceutical Sciences, 50(2), 361-369. https://doi.org/10.1590/S1984-82502014000200016