Efficacy of electrical Russian current stimulation after end-to-side neurorrhaphy of the common fibular nerve: electroneuromyography and muscle strength analysis
DOI:
https://doi.org/10.1590/1809-2950/17022626032019Keywords:
Electric Stimulation, Transcutaneous Electric Nerve Stimulation, Rats, Wistar, Peroneal NerveAbstract
Peripheral nerve injury leads to a high functional loss of muscle tissue. Thus, many studies have investigated surgical techniques, such as neurorraphies, and therapeutic resources, such as electrical stimulation, to improve the functionality of reinnervated muscle after peripheral injury. This study aims to investigate the effects of electrical stimulation with Russian Current (2,500Hz, 4ms, 10:20 sec contraction/relaxation, modulated at 10Hz and 100Hz) in the functional recovery after section and end-to-side neurorrhaphy of the peroneal nerve distal stump common to the lateral face of the tibial nerve in rats. In this study, 25 male Wistar rats with 80 days of life were used, provided by the Universidade Sagrado Coração (USC), Bauru, SP, Brazil. The animals were randomly divided into five groups: Initial Control Group (ICG), Final Control Group (FCG), Untreated Experimental Group (UEG), Endto-Side Neurorrhaphy with Russian Stimulation Group (ENRSG), and Denervated Control Group (DCG). The Russian Current was started 5 days after neurorrhaphy and applied to the cranial tibial muscle of the ENRSG, 3 times a week, totaling 36 sessions. We observed that the electrical stimulation with Russian Current (ENRSG) was effective to increase amplitude (mV) and to decrease the latency (ms) of the reinnervated muscle, besides increasing the muscle strength when compared with the denervated control group. Therefore, we concluded that the average frequency electrical stimulation (Russian current) was efficient in the functional recovery of the cranial tibial muscle after the end-lateral neurorrhaphy of the common fibular nerve.
Downloads
References
Cavalcante VEV, Montenegro EJN, Pontes NTF. Efeito da
eletroestimulação no músculo desnervado de animais: revisão
sistemática. Fisioter Mov. 2012;25(3):669-78. doi: 10.1590/
S0103-51502012000300022
Viterbo F. Neurorrafia látero-terminal: estudo experimental no
rato [tese]. Botucatu (SP): Universidade Estadual Paulista; 1992.
Rovak JM, Cederna PS, Kuzon WM. Terminolateral neurorrhaphy:
a review of the literature. J Reconstr Microsurg. 2001;17(8):615-
doi: 10.1055/s-2001-18817
Souza FI, Santos GB, Silva CF, Mattar Júnior R, Zumiotti AV.
Avaliação histológica da neurorrafia término-lateral: estudo
experimental em ratos. Acta Ortop Bras. 2011;19(3):129-31. doi:
1590/S1413-78522011000300002
Viterbo F, Trindade JC, Hoshino K, Mazzoni Neto A. Lateroterminal neurorrhaphy without removal of the epineural sheath:
experimental study in rats. Rev Paul Med. 1992;110(6):267-75.
doi: 10.1590/S1516-31801998000500005
Carvalho DCI, Rosim CG, Gama LOR, Tavares MR, Tribioli
RA. Tratamentos não farmacológicos na estimulação da
osteogênese. Rev Saúde Pública. 2002;36(5):647-54. doi:
1590/S0034-89102002000600017
Viterbo F, Trindade JC, Hoshino K, Mazzoni Neto A. Endto-side neurorraphy with removal of the epineurial sheath:
an experimental study in rats. Plastic Reconstruc Surg.
;94(7):1038-47. doi: 10.1590/s0102-865020170090000002
Ward AR, Lucas TS. Lowering of sensory, motor and paintolerance thresholds with burst duration using kHz frequency
alternating current electrical stimulation. Arch Phys Med
Rehabil. 2007;88(8):1036-41. doi: 10.1016/j.apmr.2007.04.009
Papalia I, Ronchi G, Muratori L, Mazzucco A, Magaudda L,
Geuna S. Direct muscle neurotization after end-to end and
end-to-side neurorrhaphy: an experimental study in the rat
forelimb model. Neural Regen Res. 2012;7(29):2273-8. doi:
3969/j.issn.1673-5374.2012.29.005
Udina E, Puigdemasa A, Navarro X. Passive and active exercise
improve regeneration and muscle reinnervation after peripheral
nerve injury in the rat. Muscle Nerve. 2011;43(4):500-9. doi:
1002/mus.21912
Thompson NJ, Sengelaub DR, English AW. Enhancement of
peripheral nerve regeneration due to treadmill training and
electrical stimulation is dependent on androgen receptor
signaling. Dev Neurobiol. 2014;74(5):531-40. doi: 10.1002/
dneu.22147
Nemeth PM. Electrical stimulation of denervated muscle
prevents decreases in oxidative enzymes. Muscle Nerve.
;5(2):134-9. doi: 10.1002/mus.880050210
Viterbo F, Trindade JC, Hoshino K, Mazzoni Neto A. Two endto side neurorraphies and nerve graft with removal of the
epineural sheath: experimental study in rats. Br J Plastic Surg.
;47(2):75-80. doi: 10.1590/S0102-86502012000300010
Maciel FO, Viterbo F, Chinaque LDFC, Souza BM. Effect of
electrical stimulation of the cranial tibial muscle after end-toside neurorrhaphy of the peroneal nerve in rats. Acta Cir Bras.
;28(1):39-47. doi: 10.1590/S0102-86502013000100007
Willand MP, Chiang CD, Zhang JJ, Kemp SWP, Borschel
GH, Gordon T. Daily electrical muscle stimulation enhances
functional recovery following nerve transection and repair
in rats. Neurorehabil Neural Repair. 2015;29(7):690-700. doi:
1177/1545968314562117
Rosso MPO, Rosa Júnior GM, Buchaim DV, German IJS, Pomini
KT, Souza RG, et al. Stimulation of morphofunctional repair of
the facial nerve with photobiomodulation, using the end-to-side
technique or a new heterologous fibrin sealant. J Photochem
Photobiol B. 2017;175:20-8. doi: 10.1016/j.jphotobiol.2017.08.023
Buchaim DV, Andreo JC, Ferreira Junior RS, Barraviera
B, Rodrigues AC, Macedo MC, et al. Efficacy of laser
photobiomodulation on morphological and functional repair
of the facial nerve. Photomed Laser Surg. 2017;35(8):442-9.
doi: 10.1089/pho.2016.4204
Downloads
Published
Issue
Section
License
Copyright (c) 2019 Fisioterapia e Pesquisa
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
