Comparative study regarding the efficacy and effects of 2-(4’-Thiazolyl) benzimidazole and thiodiphenilamine when used as antihelmintics in Nelore cattle

Abstract

This work describes various controlled tests that were conducted for the purpose of comparing the efficacy and effects of two antihilmintics (2-(4'-thiazolyl) -benzimidazole (thiabendazole) and thiodiphenilamine (phenothiazine) among the Nelore cattle raised on an extensive grazing in a pasture comprised of Panicum maximum (colonião grass). For such tests there was a selection of 21 heifers weighing between 128 and 227 kgs., which animals presented 200 or more Strongylides eggs per gram of feces. Those heifers were sorted out at random in three groups of seven animals each, one of which was left as a "stand by" group without any treatment at all. The two other groups were treated with phenothiazine and thiabendazole, respectively. At the end of the treatment, which lasted 25 days, four animals of each group were sacrified and a search for worms was performed in their gastrointestinal tracts. The efficacy of such treatments was noticed through the checking of worms in the feces. The efficiency of the antihelmintics was verified by means of hematological and biochemical testing of the sarum, and by weighing the animal. The results thus secured were analysed statistically.