Evaluation of a suckling-mouse-brain rabies vaccine in unvaccinated dogs studied in natural conditions

Abstract

The evaluation of a suckling-mouse-brain rabies vaccine in unvaccinated dogs was made using two different approaches. When the serum-neutralization technic was employed it was observed a slow and small rise in the median antibodies tittles being this increased followed by a fast decline as early as 45 days after vaccination. Further, was observed that immunitary reaction was more sensitive to the 2nd procedure employed: the immunofluorescence method. Using this technic the median antibodies tittles declined only after 60 days of vaccination.