COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient

Autores

  • Nicolás Ariza Ordoñez Fundación Cardioinfantil, Instituto de Cardiología, Bogotá, Colombia. Universidad del Rosario, Bogotá, Colombia http://orcid.org/0000-0003-4137-8774
  • Valeria Gomez Sepulveda Fundación Cardioinfantil, Instituto de Cardiología, Bogotá, Colombia. Universidad del Rosario, Bogotá, Colombia.
  • Lina Patricia Vargas Fundación Cardioinfantil, Instituto de Cardiología, Bogotá, Colombia. Universidad del Rosario, Bogotá, Colombia.
  • Julian Mauricio Moreno Fundación Cardioinfantil, Instituto de Cardiología, Bogotá, Colombia. Universidad del Rosario, Bogotá, Colombia. http://orcid.org/0000-0001-5991-2184

DOI:

https://doi.org/10.1590/S1678-9946202163042

Palavras-chave:

COVID-19, Skin manifestations, SARS CoV-2, Shock

Resumo

Acute generalised exanthematous pustulosis (AGEP) is an unusual cutaneous reaction, most often related with a hypersensitivity reaction to commonly used drugs. It is characterized by an abrupt onset of a pustular rash within hours or days after drug exposure and usually resolves spontaneously within 1-2 weeks after drug discontinuation. Some cases associated with systemic involvement and shock have been reported. We present the case of a severe AGEP, manifesting in association with systemic involvement and haemodynamic instability resulting in shock and multiorgan dysfunction in an adult female patient diagnosed with COVID-19 infection. There were no identifiable associated drugs, and the patient was not initiated on antimalarial drugs. Our patient improved rapidly, both hemodynamically and dermatologically with no directed therapy.

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Publicado

2021-06-14

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Como Citar

Ordoñez, N. A. ., Sepulveda, V. G. ., Vargas, L. P. ., & Moreno, J. M. (2021). COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient. Revista Do Instituto De Medicina Tropical De São Paulo, 63, e42. https://doi.org/10.1590/S1678-9946202163042