Yellow fever vaccination before and during the covid-19 pandemic in Brazil
DOI:
https://doi.org/10.11606/s1518-8787.2022056004503Palavras-chave:
Yellow Fever Vaccine, Vaccination Coverage, Immunization Programs, COVID-19, Time Series StudiesResumo
OBJECTIVE To analyze the number of yellow fever vaccine doses administered before and during the covid-19 pandemic in Brazil. METHODS This is an ecological, time series study based on data from the National Immunization Program. Differences between the median number of yellow fever vaccine doses administered in Brazil and in its regions before (from April/2019 to March/2020) and after (from April/2020 to March/2021) the implementation of social distancing measures in the country were assessed via the Mann-Whitney test. Prais-Winsten regression models were used for time series analyses. RESULTS We found a reduction in the median number of yellow fever vaccine doses administered in Brazil and in its regions: North (-34.71%), Midwest (-21.72%), South (-63.50%), and Southeast (-34.42%) (p < 0.05). Series showed stationary behavior in Brazil and in its five regions during the covid-19 pandemic (p > 0.05). Brazilian states also showed stationary trends, except for two states which recorded an increasing trend in the number of administered yellow fever vaccine doses, namely: Alagoas State (before: β = 64, p = 0.081; after: β = 897, p = 0.039), which became a yellow fever vaccine recommendation zone, and Roraima State (before: β = 68, p = 0.724; after: β = 150, p = 0.000), which intensified yellow fever vaccinations due to a yellow fever case confirmation in a Venezuelan State in 2020. CONCLUSION The reduced number of yellow fever vaccine doses administered during the covid-19 pandemic in Brazil may favor the reemergence of urban yellow fever cases in the country.
Referências
Organização Pan-Americana da Saúde. O programa de imunização no contexto da pandemia da COVID-19; versão 2. Washington, DC: OPAS; 2020 [cited 2020 Jul 24]. Available from: https://iris.paho.org/handle/10665.2/52102
Saxena S, Skirrow H, Bedford H. Routine vaccination during covid-19 pandemic response. BMJ. 2020;369:m2392. https://doi.org/10.1136/bmj.m2392
World Health Organization. Framework for decision-making: implementation of mass vaccination campaigns in the context of COVID-19: interim guidance. Geneva (CH): WHO; 2020 [cited 2021 Apr 5]. Available from: https://www.who.int/publications/i/item/WHO-2019-nCoV-Framework_Mass_Vaccination-2020.1
World Health Organization. Second round of the national pulse survey on continuity of essential health services during the COVID-19 pandemic. Geneva (CH): WHO; 2021 [cited 2021 Jun 25]. Annex 1: National pulse survey on continuity of essential health services during the COVID-19 pandemic; p.65-86. Available from: https://www.who.int/publications/i/item/WHO-2019-nCoV-EHS-continuity-survey-2021.1
Silva LLS, Lima AFR, Polli DA, Razia PFS, Pavão LFA, Cavalcanti MAFH, et al. Social distancing measures in the fight against COVID-19 in Bazil: description and epidemiological analysis by state. Cad Saude Publica. 2020;36(9):e00185020. https://doi.org/10.1590/0102-311X00185020
Gaythorpe K, Abbas K, Huber J, Karachaliou A, Thakkar N, Woodruff K, et al. Health impact of routine immunisation service disruptions and mass vaccination campaign suspensions caused by the COVID-19 pandemic: multimodel comparative analysis of disruption scenarios for measles, meningococcal A, and yellow fever vaccination in 10 low- and lower middle-income countries. medRxiv [Preprint] 2021 [posted 2021 Jan 26]. https://doi.org/10.1101/2021.01.25.21250489
Figueiredo PO, Stoffella-Dutra AG, Costa GB, Oliveira JS, Amaral CD, Santos JD, et al. Re-emergence of yellow fever in Brazil during 2016-2019: challenges, lessons learned, and perspectives. Viruses. 2020;12(11):1233. https://doi.org/10.3390/v12111233
Gaythorpe KA, Hamlet A, Jean K, Ramos DG, Cibrelus L, Garske T, et al. The global burden of yellow fever. Elife. 2021;10:e64670. https://doi.org/10.7554/eLife.64670
Chen LH, Wilson ME. Yellow fever control: current epidemiology and vaccination strategies. Trop Dis Travel Med Vaccines. 2020;6:1. https://doi.org/10.1186/s40794-020-0101-0
Cavalcante KRLJ, Tauil PL. Epidemiological characteristics of yellow fever in Brazil, 2000-2012. Epidemiol Serv Saude. 2016;25(1):11-20. https://doi.org/10.5123/S1679-49742016000100002136/2019/SVS/MS
Ministério da Saúde (BR), Secretaria de Vigilância em Saúde, Departamento de Vigilância das Doenças Transmissíveis. Anexo: Orientações técnico-operacionais para implantação da vacina febre amarela (atenuada), nas áreas sem recomendação de vacinação e atualização das indicações da vacina no Calendário Nacional de Vacinação. Brasília, DF; 2020 [cited 2021 Jun 28]. 17 p. https://sbim.org.br/images/files/ms-sei-implantacao-da-vfa-dose-de-reforco.pdf
Melo CFCA, Vasconcelos PFC, Alcantara LCJ, Araujo WN. The obscurance of the greatest sylvatic yellow fever epidemic and the cooperation of the Pan American Health Organization during the COVID-19 pandemic. Rev Soc Bras Med Trop. 2020;53:e20200787. https://doi.org/10.1590/0037-8682-0787-2020
Ministério da Saúde (BR), Secretaria de Vigilância em Saúde, Coordenação Geral de Vigilância das Arboviroses. Situação epidemiológica da febre amarela no monitoramento 2019/2020. Bol Epidemiol. 2020 [cited 2021 Jun 28];51(1):1-19. Available from: https://www.rets.epsjv.fiocruz.br/sites/default/files/arquivos/biblioteca/boletim-epidemiologico-svs-01.pdf
Kraemer MUG, Faria NR, Reiner RC Jr, Golding N, Nikolay B, Stasse S, et al. Spread of yellow fever virus outbreak in Angola and the Democratic Republic of the Congo 2015-16: a modelling study. Lancet Infect Dis. 2017;17(3):330-8. https://doi.org/10.1016/S1473-3099(16)30513-8
Yismaw AE, Assimamaw NT, Bayu NH, Mekonen SS. Incomplete childhood vaccination and associated factors among children aged 12-23 months in Gondar city administration, Northwest, Ethiopia 2018. BMC Res Notes. 2019;12(1):241. https://doi.org/10.1186/s13104-019-4276-2
Arroyo LH, Ramos ACV, Yamamura M, Weiller TH, Crispim JA, Cartagena-Ramos D, et al. [Areas with declining vaccination coverage for BCG, poliomyelitis, and MMR in Brazil (2006-2016): maps of regional heterogeneity]. Cad Saude Publica. 2020;36(4):e00015619. Portuguese. https://doi.org/10.1590/0102-311X00015619
Césare N, Mota TF, Lopes FFL, Lima ACM, Luzardo R, Quintanilha LF, et al. Longitudinal profiling of the vaccination coverage in Brazil reveals a recent change in the patterns hallmarked by differential reduction across regions. Int J Infect Dis. 2020;98:275-80. https://doi.org/10.1016/j.ijid.2020.06.092
Vieira EW, Pimenta AM, Montenegro LC, Silva TMR. Structure and location of vaccination services influence the availability of the triple viral in Brazil. REME Rev Min Enferm. 2020;24:e1325. https://doi.org/10.5935/1415-2762.20200062
Pacheco FC, França GVA, Elidio GA, Domingues CMAS, Oliveira C, Guilhem DB. Trends and spatial distribution of MMR vaccine coverage in Brazil during 2007–2017. Vaccine. 2019;37(20):2651-5. https://doi.org/10.1016/j.vaccine.2019.04.019
Mantel C, Cherian T. New immunization strategies: adapting to global challenges. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020;63(1):25-31. https://doi.org/10.1007/s00103-019-03066-x
Antunes JLF, Cardoso MRA. Using time series analysis in epidemiological studies. Epidemiol Serv Saude. 2015;24(3):565-76. https://doi.org/10.5123/S1679-49742015000300024
Chen Y. Spatial autocorrelation approaches to testing residuals from least squares regression. PLoS One. 2016;11(1):e0146865. https://doi.org/10.1371/journal.pone.0146865
Ministério da Saúde (BR), Secretaria de Vigilância em Saúde. Informe quinzenal sarampo – Brasil, semanas epidemiológicas 43 de 2020 a 1 de 2021. Bol Epidemiol. 2021 [cited 2021 Jun 28];52(4):1-24. Available from: https://www.gov.br/saude/pt-br/media/pdf/2021/fevereiro/11/boletim_epidemiologico_svs_4.pdf
Instituto Brasileiro de Geografia e Estatística. Sinopse do Censo Demográfico 2010. Rio de Janeiro: IBGE; 2010 [cited 2021 Aug 1]. Available from: https://censo2010.ibge.gov.br/sinopse/index.php
Silva FS, Barbosa YC, Batalha MA, Ribeiro MRC, Simões VMF, Branco MRFC, et al. Incompletude vacinal infantil de vacinas novas e antigas e fatores associados: coorte de nascimento BRISA, São Luís, Maranhão, Nordeste do Brasil. Cad Saude Publica. 2018;34(3):e00041717. https://doi.org/10.1590/0102-311X00041717
Kerr L, Kendall C, Silva AAM, Aquino EML, Pescarini JM, Almeida RLF, et al. COVID-19 in Northeast Brazil: achievements and limitations in the responses of the state governments. Cienc Saude Colet. 2020;25 Suppl 2:4099-120. https://doi.org/10.1590/1413-812320202510.2.28642020
Noronha KVMS, Guedes GR, Turra CM, Andrade MV, Botega L, Nogueira D, et al. The COVID-19 pandemic in Brazil: analysis of supply and demand of hospital and ICU beds and mechanical ventilators under different scenarios. Cad Saude Publica. 2020;36(6):e00115320. https://doi.org/10.1590/0102-311X00115320
Lemos DRQ, D’Angelo SM, Farias LABG, Almeida MM, Gomes RG, Pinto GP, et al. Health system collapse 45 days after the detection of COVID-19 in Ceará, Northeast Brazil: a preliminary analysis. Rev Soc Bras Med Trop. 2020;53:e20200354. https://doi.org/10.1590/0037-8682-0354-2020
Ritchie A, Esteban Ortiz-Ospina, Diana Beltekian, Edouard Mathieu. Coronavirus (COVID-19) vaccinations. Our World in Data. 2021 [cited 2021 Mar 29]. Available from: https://ourworldindata.org/covid-vaccinations
Medina MG, Giovanella L, Bousquat A, Mendonça MHM, Aquino R. Primary healthcare in times of COVID-19: what to do? Cad Saude Publica. 2020;36(8):e00149720. https://doi.org/10.1590/0102-311x00149720
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Copyright (c) 2022 Tércia Moreira Ribeiro da Silva, Ana Carolina Micheletti Gomide Nogueira de Sá, Elton Junio Sady Prates, Daiana Elias Rodrigues, Thales Philipe Rodrigues da Silva, Fernanda Penido Matozinhos, Ed Wilson Rodrigues Vieira
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