A função da prostaglandina F2α na ovulação e na liberação de LH em vacas

Autores

  • Natália Ávila de Castro Universidade Federal de Pelotas, Pelotas – RS, Brazil https://orcid.org/0000-0002-7710-6044
  • Carlos Eduardo Porciuncula Leonardi University of Saskatchewan, Saskatoon – SK, Canada
  • Jaswant Singh University of Saskatchewan, Saskatoon – SK, Canada
  • Augusto Schneider Universidade Federal de Pelotas, Pelotas – RS, Brazil
  • Paulo Bayard Gonçalves Universidade Federal de Santa Maria, Santa Maria – RS, Brazil
  • Fernando Caetano Oliveira Universidade Federal de Pelotas, Pelotas – RS, Brazil
  • Camila Amaral D’Ávila Universidade Federal de Pelotas, Pelotas – RS, Brazil
  • Rogério Ferreira Universidade Estadual de Santa Catarina, Chapecó – SC, Brazil
  • Bernardo Garziera Gasperin Universidade Federal de Pelotas, Pelotas – RS, Brazil
  • Elizângela Mírian Moreira Embrapa-Empresa Brasileira de Pesquisa Agropecuária, Porto Velho – RO, Brazil
  • Jéssica de Souza Andrade Bionorte-Rede de Biodiversidade e Biotecnologia da Amazônia Legal, Programa de Pós-graduação em Biodiversidade e Biotecnologia da Amazônia Legal, Porto Velho – RO, Brazil
  • Luiz Francisco Machado Pfeifer EmbrapaEmbrapa-Empresa Brasileira de Pesquisa Agropecuária, Porto Velho – RO, Brazil https://orcid.org/0000-0003-2069-951X

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.2021.175001

Palavras-chave:

Vaca, Ovário, Pituitária, Prostaglandina, Reprodução

Resumo

O objetivo deste estudo foi avaliar o papel da prostaglandina F2α (PGF) na ovulação. No Experimento 1, as vacas foram alocadas aleatoriamente em dois tratamentos para receber 150 μg de d-Cloprostenol (Grupo PGF, n = 12) ou 2 mL de NaCl 0,9% (Grupo Controle, n = 11) e os CIDR, foram removidos 4 dias depois. Nenhuma vaca ovulou nos grupos Controle e PGF. No Experimento 2, as vacas foram separadas aleatoriamente em dois grupos experimentais para receber 4 injeções de 150 μg de d-Cloprostenol (n = 9) ou 2 mL de NaCL 0,9% (n = 9). Não foi observada ovulação em nenhum dos animais deste experimento. No Experimento 3, vacas ovariectomizadas receberam três injeções de 300μg de análogo de PGF (Grupo PGF, n = 5), 100μg de Lecirelina (Grupo GnRH, n = 5) ou 2 mL de PBS (Grupo Controle, n = 4). A concentração de LH foi maior (P <0,0001) nas vacas do grupo GnRH do que nos grupos PGF e Controle. No Experimento 4, vacas com folículos pré-ovulatórios (> 11,5 mm) foram tratadas com solução salina (Grupo Controle, n = 6), Lecirelina (Grupo GnRH, n = 7) ou Cloprostenol Sódico (Grupo PGF, n = 6). Houve um aumento significativo na área vascular dos folículos de 0 a 24h nos tratamentos com GnRH e PGF. Em conclusão, a PGF não foi capaz de induzir ovulação em vacas com alta ou baixa concentração plasmática de progesterona. Além disso, a PGF sozinha não foi capaz de induzir a liberação de LH e a luteinização do folículo, mas aumentou a vascularização folicular.

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Publicado

2021-04-01

Edição

v. 58 (2021)

Seção

ARTIGO COMPLETO

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Copyright (c) 2021 Brazilian Journal of Veterinary Research and Animal Science

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1.
Castro N Ávila de, Leonardi CEP, Singh J, Schneider A, Gonçalves PB, Oliveira FC, et al. A função da prostaglandina F2α na ovulação e na liberação de LH em vacas. Braz. J. Vet. Res. Anim. Sci. [Internet]. 1º de abril de 2021 [citado 18º de maio de 2024];58:e175001. Disponível em: https://www.journals.usp.br/bjvras/article/view/175001