Pharmaceutical care reducing the impact of the COVID-19 pandemic on the cardiovascular health of hypertensive and diabetic patients

Authors

DOI:

https://doi.org/10.11606/issn.2176-7262.rmrp.2023.209939

Keywords:

Hypertension, Diabetes mellitus, Pharmaceutical services, COVID-19

Abstract

Introduction: The COVID-19 pandemic has impacted the provision of health services to patients with chronic diseases, and the Medication Therapy Management, an integral part of pharmaceutical care can lead to an improvement in clinical parameters impacted by the pandemic. The objective of this study was to assess the clinical impact of
MTM-PC on systemic arterial hypertension and diabetes mellitus (DM) in comparison with the changes imposed by the COVID-19 pandemic in the primary healthcare scope. Methods: This is a quasi-experimental, single-arm, before-and-after study, with data collection from July 1, 2019 to October 31, 2022. Data from patients at the pharmaceutical
services, of the teaching-Pharmacy of UFJF, were included in the study and were divided into pre-pandemic and pandemic period, considering baseline data and the data related to the reintroduction of face-to-face care in the office as an endpoint.. Data were collected on blood pressure, lipidic profile, glycemia, use of statins and acetylsalicylic acid, cardiovascular risk, and psychosocial data, consequences of social isolation on mental health, medication prescription and life habits. Data were analyzed using the MINITAB v19 software, considering a significance level of 5%. Results: During the pandemic without MTM-PC it was found that blood pressure and HDL increased comparing the pre-pandemic with the pandemic without MTM-PC, respectively, SBP 117.5±8.86 and 134.75±12.43; DBP 71.25±3.54 and 83.25±11.65; HDL 45.25±7.80 and 52.38±12.52. Comparatively, it was verified that the blood pressure values were maintained and, the MTM-PC changed parameters like HbA1c 7.890±1.798, [p=0.028] and 7.325±1.30; HDL48.00±6.00 and 59.00±10.56, [p=0.020]. There was a change in both mean of cardiovascular risk, the global scale 13.69±8.08 to 22.38±7.28 and the optimized scale 8.35±6.71 to 16.10±5.83, [p=0.38], with a break in the trend of increased risk with the MTM-PC. The therapeutic load of drugs used for hypertension and diabetes remained below the limit value of 75%. Conclusion: There was evidence that the pandemic changed parameters such as blood pressure and cardiovascular risk. Additionally, the MTM-PC may be able to reduce the impact of the pandemic on glycated hemoglobin, improve HDL cholesterol levels and break a trend of increased cardiovascular risk.

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Author Biographies

  • Nathália Castilho Roque, Universidade Federal de Juiz de Fora. Faculdade de Farmácia Juiz de Fora, Minas Gerais, Brasil

    Residente farmacêutica

  • Vitor Franco Machado, Universidade Federal de Juiz de Fora. Faculdade de Farmácia Juiz de Fora, Minas Gerais, Brasil

    Farmacêutico

  • Maurilio Souza Cazarim, Universidade Federal de Juiz de Fora. Faculdade de Farmácia Juiz de Fora, Minas Gerais, Brasil

    Professor, PhD

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Published

— Updated on 2023-12-18

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How to Cite

1.
Roque NC, Machado VF, Cazarim MS. Pharmaceutical care reducing the impact of the COVID-19 pandemic on the cardiovascular health of hypertensive and diabetic patients. Medicina (Ribeirão Preto) [Internet]. 2023 Dec. 18 [cited 2024 May 15];56(4):e-209939. Available from: https://www.journals.usp.br/rmrp/article/view/209939